Conservative MPs from the West Briton area voted in favour of military action in Syria “in principle” in a historic parliamentary debate.
But Prime Minister David Cameron failed to garner enough support and suffered a humiliating defeat.
Helston MP Andrew George was among those who voted against his Lib Dem party leadership and against military intervention.
Camborne and Redruth MP George Eustice (Con) said: “The proposed intervention in Syria did not compare with Iraq where Tony Blair sent tens of thousands of troops to depose a regime, occupy a country and then attempt to build a democracy from scratch.
“The mission in Syria would have had one clear and modest objective: to prevent the use of chemical weapons and it would not have involved the commitment of troops on the ground. Parliament should have supported it."
Mr Cameron broke off his holiday in Cornwall to recall parliament to discuss a possible military strike in response to a suspected chemical weapons attack in Syria.
Truro and Falmouth MP Sarah Newton (Con) said: “‘Like everyone else I was horrified to see the footage of the chemical weapons attacks that took place in Syria last month.
“I feel strongly that we cannot stand by and let such attacks, which are against international law, take place again.
“Last week I voted for our Government to respond to the calls for help from countries in the region, using the UN process to send a strong message to the Syrian regime that they should not use chemical weapons, that there are consequences if they do.”
The Prime Minister lost by 13 votes as MPS appeared to be haunted by the UK’s experience in Iraq.
Mr George, Lib Dem MP for West Cornwall, said he voted against military intervention as it could escalate the already desperate situation in Syria.
He said: “No matter what I may think about the appalling Assad regime and the almost certainty that they have used chemical weapons to kill hundreds and injure thousands of their own people is not sufficient to persuade me that the UK should engage in or support military strikes in Syria.
“Yes, bomb them with diplomacy, inspectors, humanitarian aid, shelter and support, but recent history should now have taught us that military engagement merely changes the problem, it doesn’t resolve it.”