UPDATE: 6.30pm: Two people have been left with "serious life-threatening injuries" following a two vehicle collision on the A38 near Tideford earlier today.
A truck and a Jaguar car collided, with two people trapped in the Jaguar.
According to police reports the Jaguar left the carriageway as a result of the collision.
The Jaguar was travelling towards Plymouth, whilst the HGV was travelling in the opposite direction.
One fire crew from Liskeard and a rescue tender from Bodmin attended and freed two people trapped in the Jaguar.
Both were taken to Derriford Hospital in Plymouth by ambulance with potentially life-threatening injuries.
The male driver of the dark green Jaguar XJ Executive, believed to be in his 60s, has suffered leg, chest and possible hip injuries.
He is said to be in a very serious condition.
The A38 has now been re-opened after police officers investigated the scene.
EARLIER: The A38 is closed in both directions at Carkeel following a serious road traffic collision involving a car and a lorry.
Police are urging drivers to avoid the area following the crash, which took place near the B3249 junction at St German at around 10.20 this morning.
Fire crews cut two people from the car. Police say they have both been taken to Derriford hospital. The extent of their injuries is not yet known.
The driver of the lorry is not thought to be seriously hurt.
A police spokesman said: “The A38 has been closed at Carkeel due to a serious road traffic collision. "Diversions are in place but please avoid the area if you can.”