Newlyn's Jack Nowell will make his debut for England in Saturday's RBS 6 Nations opener against France.
The Exeter Chiefs winger has been handed the number 14 shirt, replacing Chris Ashton.
He will be joined in the side by fellow debutant Luther Burrell of Northampton Saints.
England Head Coach Stuart Lancaster said: “We can’t wait for Saturday. We’ve had a good two weeks and all the players have pushed hard for selection.
“Congratulations to Jack and Luther who deserve their chance, as does Jonny May starting his first RBS 6 Nations game.
"It’s also great to see Brad Barritt back with his experience and leadership in the 23, while Alex Goode will give us good cover at 15 and 10.
“We felt the pack went well in the autumn and it’s right to leave it unchanged but we have some quality players, including two British Lions in Tom and Mako, to come on.”
England team to play France, RBS 6 Nations, Stade de France, Saturday, 5pm:
15 Mike Brown (Harlequins, 21 caps)
14 Jack Nowell (Exeter Chiefs, uncapped)
13 Luther Burrell (Northampton Saints, uncapped)
12 Billy Twelvetrees (Gloucester Rugby, 8 caps)
11 Jonny May (Gloucester Rugby, 1 cap)
10 Owen Farrell (Saracens, 19 caps)
9 Danny Care (Harlequins, 42 caps)
1 Joe Marler (Harlequins, 15 caps)
2 Dylan Hartley (Northampton Saints, 50 caps)
3 Dan Cole (Leicester Tigers, 43 caps)
4 Joe Launchbury (London Wasps, 14 caps)
5 Courtney Lawes (Northampton Saints, 25 caps)
6 Tom Wood (Northampton Saints, 23 caps)
7 Chris Robshaw (Harlequins, capt, 20 caps)
8 Billy Vunipola (Saracens, 5 caps)
16 Tom Youngs (Leicester Tigers, 12 caps)
17 Mako Vunipola (Saracens, 10 caps)
18 Henry Thomas (Sale Sharks, 2 caps)
19 Dave Attwood (Bath Rugby, 5 caps)
20 Ben Morgan (Gloucester Rugby, 15 caps)
21 Lee Dickson (Northampton Saints, 12 caps)
22 Brad Barritt (Saracens, 16 caps)
23 Alex Goode (Saracens, 13 caps)
To watch Stuart Lancaster's interview on team selection visit rfu.com
*Send you good luck messages to Jack using the comment form below, or via Twitter using the #goodluckjack hashtag.